∵AB2+AC2=62+82=100=BC2,∴△ABC是直角三角形,△ABC的面积= 1 2 ×6×8=24cm2,∵D、E、F分别是各边中点,∴△DEF的周长= 1 2 ×(6+8+10)=12cm,△DEF的面积= 1 4 ×24=6cm2.故答案为:12cm;6cm2.